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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD1
All Species:
30.3
Human Site:
S499
Identified Species:
44.44
UniProt:
Q13393
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13393
NP_001123553.1
1074
124184
S499
H
R
L
T
D
V
G
S
V
K
R
V
T
S
G
Chimpanzee
Pan troglodytes
XP_526380
1125
128795
S562
K
L
V
I
I
D
Q
S
V
A
F
V
G
G
I
Rhesus Macaque
Macaca mulatta
XP_001085464
1074
124020
S499
H
R
L
T
D
V
G
S
V
K
R
V
T
S
G
Dog
Lupus familis
XP_545291
1075
123911
S499
H
R
L
T
D
V
G
S
V
K
R
V
T
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z280
1074
123950
S499
H
R
L
T
D
V
G
S
V
K
R
V
T
S
G
Rat
Rattus norvegicus
P70496
1074
123795
S499
H
R
L
T
D
V
G
S
V
K
R
V
T
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513744
295
33781
Chicken
Gallus gallus
XP_422793
1072
123414
S497
H
R
L
T
D
V
G
S
V
K
R
M
G
A
V
Frog
Xenopus laevis
NP_001129642
1039
119219
F477
V
I
D
Q
S
V
A
F
V
G
G
I
D
L
A
Zebra Danio
Brachydanio rerio
NP_001153567
1022
117847
H459
S
V
Y
L
W
A
H
H
E
K
I
V
V
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137610
1364
155352
S736
H
R
L
T
D
L
G
S
I
S
T
S
S
F
S
Honey Bee
Apis mellifera
XP_001121004
1135
129725
N528
H
R
L
I
D
L
G
N
T
H
Q
S
S
I
Y
Nematode Worm
Caenorhab. elegans
NP_494939
1427
163517
S676
H
L
L
T
D
L
G
S
V
Q
Y
S
G
A
H
Sea Urchin
Strong. purpuratus
XP_784455
790
90080
G292
Q
R
I
A
F
I
G
G
I
D
I
C
Y
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
S469
R
Y
P
D
H
L
S
S
G
I
Y
L
W
S
H
Baker's Yeast
Sacchar. cerevisiae
P36126
1683
195185
C684
P
V
R
T
N
S
F
C
K
F
L
V
D
G
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
97.8
91
N.A.
91
90.6
N.A.
22
79.4
75.6
66.6
N.A.
34.8
40.3
35.9
35.1
Protein Similarity:
100
92
99
95.1
N.A.
95.6
95.6
N.A.
24.8
88.8
86.3
78.3
N.A.
50.9
57.7
51
49.5
P-Site Identity:
100
20
100
93.3
N.A.
100
100
N.A.
0
73.3
13.3
13.3
N.A.
46.6
33.3
46.6
13.3
P-Site Similarity:
100
26.6
100
93.3
N.A.
100
100
N.A.
0
86.6
20
13.3
N.A.
66.6
60
66.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.6
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
7
7
0
0
7
0
0
0
13
7
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% C
% Asp:
0
0
7
7
57
7
0
0
0
7
0
0
13
0
7
% D
% Glu:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
7
0
7
7
0
7
7
0
0
7
0
% F
% Gly:
0
0
0
0
0
0
63
7
7
7
7
0
19
25
32
% G
% His:
57
0
0
0
7
0
7
7
0
7
0
0
0
0
13
% H
% Ile:
0
7
7
13
7
7
0
0
13
7
13
7
0
13
7
% I
% Lys:
7
0
0
0
0
0
0
0
7
44
0
0
0
0
0
% K
% Leu:
0
13
57
7
0
25
0
0
0
0
7
7
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
7
0
0
7
0
0
7
7
0
0
0
0
% Q
% Arg:
7
57
7
0
0
0
0
0
0
0
38
0
0
0
13
% R
% Ser:
7
0
0
0
7
7
7
63
0
7
0
19
13
32
7
% S
% Thr:
0
0
0
57
0
0
0
0
7
0
7
0
32
0
0
% T
% Val:
7
13
7
0
0
44
0
0
57
0
0
50
7
0
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
7
7
0
0
0
0
0
0
0
13
0
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _